Turmeric Curcumin 95 | Joint & Inflammation Support

Nature's Sunshine Turmeric Curcumin harnesses the power of Turmeric extract to promote a healthy inflammatory response. This formula delivers both Turmeric root and higher levels of the antioxidant-rich Turmeric extract — providing 1,100 mg of Turmeric extract and 1,000 mg of curcuminoids per serving. One serving is equivalent to 32,000 mg of whole root Turmeric.

Curcuminoids are the primary active compounds obtained from the rhizomes of Turmeric (Curcuma longa L.), the yellow curry spice that has been safely used for centuries in Indian Ayurvedic medicine. As the principal bioactive polyphenol, Curcumin has been extensively investigated for its capacity to modulate multiple signaling pathways involved in regulating inflammatory responses and oxidative stress.

This Turmeric Curcumin 95 formula is clinically studied and enhanced with Black pepper extract to improve bioavailability and absorption — addressing one of the most significant challenges with standard Curcumin supplements. If you have questions about whether this formula fits your wellness goals, our naturopath is available for a free consultation.

Curcumin exerts its core anti-inflammatory effects mainly by inhibiting the activation of the NF-κB signaling pathway, regulating the MAPK/ERK phosphorylation cascade, and modulating the JAK/STAT pathway. It acts by reducing the production of inflammatory cytokines such as TNF-α and IL-1β, while also suppressing COX-2 and LOX enzymes responsible for producing prostaglandins and leukotrienes.

On the antioxidant side, Curcumin activates the Keap1-Nrf2/ARE transcriptional pathway, which upregulates endogenous cytoprotective enzymes. Multiple human randomized controlled trials and meta-analyses show that Curcumin supplementation may measurably raise total antioxidant capacity (TAC), superoxide dismutase (SOD), catalase, and glutathione, while lowering the lipid-peroxidation marker malondialdehyde (MDA).

A central challenge with Curcumin is its inherently poor oral bioavailability due to low water solubility, rapid metabolism, and fast systemic elimination. That's why this formula includes Black pepper extract — research suggests that co-administration with piperine may increase Curcumin bioavailability by up to 2,000% in humans.

This Turmeric Curcumin 95 formula is designed for adults seeking natural support for a healthy inflammatory response. It may be especially relevant for those looking to support joint comfort, flexibility, and mobility — research in osteoarthritis populations consistently shows improvements in pain, stiffness, and physical function with Curcumin supplementation.

It may also appeal to individuals interested in antioxidant defense against oxidative stress, as well as those looking to support skin, brain, gut, and immune system health. The formula may promote healthy microbiome balance as an added benefit.

This product is non-GMO and comes in VegCaps, making it suitable for those seeking plant-based capsule options. If you're unsure whether this formula is right for your specific needs — particularly if you take medications — our naturopath offers free consultations and can help you make an informed decision.

Take 2 VegCaps daily. Each bottle contains 60 capsules, providing a 30-day supply at the recommended serving size.

Important safety note: While Curcumin is generally well tolerated at standard supplemental doses, individuals taking anticoagulant or antiplatelet medications should exercise caution, as Curcumin may affect platelet aggregation and cytochrome P450 enzymes. Piperine from the Black pepper extract may also increase plasma concentrations of certain co-administered medications by inhibiting CYP3A4 and P-glycoprotein. If you take prescription medications, consult a healthcare professional before use.