Nature’s Way Chlorofresh Liquid Chlorophyll Guide
Explore Nature's Way Chlorofresh Liquid Chlorophyll — how sodium copper chlorophyllin supports blood cleansing, immune response, and whole body wellness.
Nature's Way Chlorofresh Liquid Chlorophyll: A Closer Look
Nature's Way Chlorofresh Liquid Chlorophyll is a 32-oz liquid formula built around sodium copper chlorophyllin — a water-soluble derivative of the green pigment that powers photosynthesis in every leaf and blade of grass. Chlorophyll nourishes plant life by converting the sun's rays to energy, but it also nourishes human life by supporting natural blood cleansing processes.
Most "Chlorophyll water" and liquid supplement products sold commercially are not natural Chlorophyll from food, but rather chlorophyllin — a semisynthetic sodium copper salt derivative developed to be water-soluble, since natural Chlorophyll is fat-soluble and does not dissolve into water cleanly. In this formulation, the central magnesium atom of natural Chlorophyll is replaced by copper, producing a stable, water-soluble compound that mixes effortlessly into a glass of cold water.
This formula also includes a small amount of spearmint aerial parts oil, contributing to the pleasant taste profile. Together, these ingredients deliver a daily liquid that supports natural blood-cleansing processes, encourages proper immune response, strengthens the body on a cellular and molecular level, and acts as a natural deodorizer.
The Science Behind Chlorophyllin
Chlorophyllin's bioactivity stems from its porphyrin ring structure — the same type of ring found in hemoglobin, just with copper at the center instead of iron. This chemical structure allows chlorophyllin to function as a hydrogen donor, helping to stop chain oxidation processes and scavenge free radicals. Research suggests chlorophyllin presents significant antioxidant activity through chelation of reactive ions and prevention of DNA damage and lipid peroxidation.
One of the most well-studied properties of chlorophyllin is its ability to form tight molecular complexes with certain chemicals known or suspected to cause harm — including polyaromatic hydrocarbons found in tobacco smoke, some heterocyclic amines found in cooked meat, and aflatoxin B1. Research suggests this binding may interfere with gastrointestinal absorption, reducing the amount that reaches susceptible tissues.
Studies also suggest chlorophyllin may support the body's natural detoxification pathways by inhibiting cytochrome P450 enzymes and inducing phase 2 cytoprotective genes — a complementary detoxification system in mammalian cells. This dual mechanism is part of why chlorophyllin has traditionally been valued as an internal cleanser.
If you have questions about how chlorophyllin fits into your personal wellness routine, our naturopath offers free consultations and is happy to walk you through the details.
Key Ingredients

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Who Is This Formula For?
Nature's Way Chlorofresh Liquid Chlorophyll is designed for adults looking for daily support in three key areas: blood health, immune system function, and whole-body cleansing. If you're drawn to the idea of an easy, refreshing daily green tonic that mixes right into a glass of water, this liquid format makes it simple to incorporate into any routine.
Those interested in supporting their body's natural detoxification processes may find chlorophyllin particularly relevant, given its well-documented ability to bind certain environmental toxins in the GI tract. Traditionally, Chlorophyll-rich preparations have also been valued by people seeking internal freshness — chlorophyllin has been used as a natural internal deodorizer for over 50 years.
Anyone exploring whether a Chlorophyll supplement fits their wellness goals is welcome to take advantage of our free naturopathic consultations. Our naturopath can help you understand how this formula might complement your individual health picture.
How to Take Nature's Way Chlorofresh Liquid Chlorophyll
Take 2 tablespoons (30mL) in an 8 fl oz glass of cold water daily. Refrigerate after opening.
Each 30 mL serving delivers 90 mg of sodium copper chlorophyllin. The liquid format makes it easy to stir into cold water for a refreshing daily green drink. Many people enjoy adding it to their morning routine as a simple way to start the day.
A note on what to expect: When taken orally, supplemental chlorophyllin may cause green discoloration of urine or feces, or yellow or black discoloration of the tongue. These are harmless cosmetic effects that have been reported over more than 50 years of clinical use. Natural chlorophylls are not known to be toxic, and no toxic effects have been attributed to chlorophyllin despite decades of human use.
Since the safety of Chlorophyll or chlorophyllin supplements has not been tested in pregnant or lactating women, they should be avoided during pregnancy and lactation. Individuals with rare disorders of copper metabolism, such as Wilson's disease, should limit exposure to copper additives, including supplemental sodium copper chlorophyllin.
Written by Greg Howlett
Frequently asked questions
Is Nature's Way Chlorofresh Liquid Chlorophyll actual Chlorophyll or chlorophyllin?
The active ingredient is sodium copper chlorophyllin — a semisynthetic, water-soluble derivative of natural Chlorophyll. In this form, the central magnesium atom of plant Chlorophyll is replaced by copper and the phytol tail is removed, making it dissolve cleanly in water. Most Liquid Chlorophyll supplements on the market use this same water-soluble form rather than natural fat-soluble Chlorophyll.
Why does Liquid Chlorophyll turn my urine or stool green?
Green discoloration of urine or feces is a well-known and harmless cosmetic effect of taking chlorophyllin orally. Some people also notice yellow or black discoloration of the tongue. These effects have been reported over more than 50 years of clinical use and are not a safety concern. Chlorophyllin may also cause false positive results on guaiac card tests for occult blood, so let your healthcare provider know if you're taking it before such testing.
How does chlorophyllin support the body's natural cleansing processes?
Research suggests chlorophyllin can form tight molecular complexes with certain chemicals in the GI tract — including polyaromatic hydrocarbons and aflatoxin B1 — potentially reducing their absorption into the body. A landmark clinical trial found that chlorophyllin supplementation produced a 55% reduction in urinary aflatoxin-DNA adduct biomarkers compared to placebo. It may also support detoxification pathways by inducing phase 2 cytoprotective enzymes. The broader concept of a 'whole body cleanse' through Chlorophyll has deep roots in traditional use and naturopathic practice.
Is chlorophyllin safe for long-term daily use?
Natural chlorophylls are not known to be toxic, and no toxic effects have been attributed to chlorophyllin despite more than 50 years of clinical use in humans. However, pregnant or lactating women should avoid Chlorophyll supplements since safety has not been established for these groups. Individuals with Wilson's disease or other copper metabolism disorders should also limit exposure. If you're on any medications — particularly methotrexate or other chemotherapy agents — speak with a healthcare provider, as an isolated case of delayed methotrexate clearance has been reported with a Chlorophyll-containing product.
Does chlorophyllin actually help with body odor?
Chlorophyllin has been used as an internal deodorant since the 1950s. A 1980 study found it was helpful in controlling body and fecal odors in 62 geriatric nursing home patients, and a separate study showed oral chlorophyllin significantly decreased urinary trimethylamine in patients with trimethylaminuria. However, the evidence for deodorizing benefits in healthy individuals is largely drawn from small, older studies. Our naturopath can discuss whether this benefit is relevant to your situation during a free consultation.
How is the Chlorophyll in this supplement different from eating green vegetables?
Green vegetables like spinach, kale, and lettuce contain natural Chlorophyll a and b, which are fat-soluble. This supplement uses sodium copper chlorophyllin — a water-soluble derivative that mixes easily into water. Research estimates daily dietary Chlorophyll intake from vegetables at 26–86 mg per day, with only about 5% bioavailability. Natural chlorophylls undergo significant transformation during digestion, with most absorbable forms being pheophytins. Chlorophyllin provides a concentrated, convenient source in a form specifically designed for water solubility.
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