Nature Made Magnesium Complex with D3 and Zinc
Discover how Nature's Sunshine Magnesium Complex with citrate & malate supports heart health, the nervous system, and muscles. 184 mg per 2-capsule serving.
Nature Made Magnesium Complex with D3 and Zinc: What It Is and Why It Matters
If you're searching for a nature made Magnesium Complex with d3 and zinc, you've likely recognized just how critical Magnesium is for everyday well-being. Nature's Sunshine Magnesium Complex is a focused Magnesium supplement that delivers 184 mg of Magnesium per two-capsule serving in two highly soluble organic forms — Magnesium citrate and Magnesium malate — chosen specifically for optimum effectiveness and absorption.
Magnesium is the fourth most abundant cation in the human body and serves as a cofactor in more than 300 enzyme systems that regulate everything from energy production and muscle contraction to nerve signaling and cardiovascular rhythm. Despite its importance, it is estimated that between 56 and 68% of Americans do not obtain enough Magnesium in their daily diet to meet the Recommended Dietary Allowance. That widespread gap is one reason so many people turn to a quality Magnesium Complex.
This formula is designed to support the cardiovascular system, help brain, kidney, and heart functions, and provide the Magnesium your muscles and nerves need to function properly. The 100-capsule bottle makes it easy to maintain a consistent daily routine.
Why Citrate and Malate: Two Highly Soluble Forms of Magnesium
Not all Magnesium supplements are created equal. Magnesium supplements are broadly categorized into organic and inorganic compounds. Organic forms — such as citrate, malate, glycinate, and lactate — involve Magnesium chelated to organic molecules, and they are generally more soluble and have higher bioavailability than inorganic forms like Magnesium oxide.
Magnesium Complex combines Magnesium citrate and Magnesium malate, both organic forms. Research shows that Magnesium citrate has high solubility even in water (55%) and is substantially more soluble than Magnesium oxide in all states of acid secretion. This matters because higher solubility translates to more efficient absorption in your digestive tract.
By pairing two complementary organic forms, this formula is described as highly soluble — an important quality for anyone who wants to make the most of each capsule. If you have questions about which form of Magnesium is right for your individual needs, our naturopath is available for a free consultation.
Key Ingredients

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Who Is Magnesium Complex For?
This formula is a good fit for a wide range of adults, but certain groups may find it especially relevant. Older adults are more susceptible to Magnesium deficiency due to decreased absorption from food, increased medication use (diuretics can deplete Magnesium), and potential dietary restrictions. Men older than 70 and teenage girls are among those most likely to have low intakes.
People who take proton pump inhibitors (PPIs), loop or thiazide diuretics, or certain antibiotics long-term should be aware that these medications can affect Magnesium status. Individuals with type 2 diabetes, gastrointestinal disorders, or alcohol dependence are also at elevated risk for Magnesium inadequacy.
Active individuals may appreciate that exercise can increase Magnesium requirements by 10–20%, and research suggests Magnesium supplementation may help reduce muscle soreness and support recovery. Anyone looking for cardiovascular, nervous system, or musculoskeletal support — or who simply suspects their diet falls short of the 310–420 mg daily RDA — may want to consider a well-absorbed Magnesium Complex like this one.
If you're not sure whether supplemental Magnesium is right for you, or you have questions about how it may interact with your current medications, our naturopath offers free consultations and is happy to help you sort things out.
How to Take Magnesium Complex
Take 2 capsules twice daily with a meal.
Each two-capsule serving provides 184 mg of Magnesium. The Recommended Dietary Allowance for Magnesium is 400–420 mg/day for adult men and 310–320 mg/day for adult women, so two servings daily — along with the Magnesium you get from foods like leafy greens, nuts, seeds, and whole grains — can help you work toward meeting your daily needs.
Important timing notes: If you take bisphosphonates (such as alendronate), separate them from Magnesium by at least 2 hours. If you take tetracycline or quinolone antibiotics, take the antibiotic at least 2 hours before or 4–6 hours after Magnesium to avoid absorption interference. Magnesium may also reduce the absorption of gabapentin by approximately 20%.
Safety Considerations and Drug Interactions
Magnesium supplements are generally well tolerated. The most common side effects are stomach-related — nausea, cramping, or softened stool — and these tend to occur at higher doses and are more common with inorganic forms like Magnesium oxide. Because this formula uses organic citrate and malate forms, gastrointestinal comfort may be improved.
The Tolerable Upper Intake Level (UL) set by the Food and Nutrition Board is 350 mg of Magnesium from supplements only (this does not include Magnesium from food). Hypermagnesemia from supplemental intake is rare in individuals with normal kidney function, as the kidneys efficiently excrete excess Magnesium. Risk is substantially elevated in individuals with impaired renal function.
Several medications can interact with Magnesium status. Loop and thiazide diuretics deplete Magnesium through increased urinary excretion, while potassium-sparing diuretics reduce Magnesium loss. Prescription proton pump inhibitors taken for prolonged periods (typically more than a year) can cause hypomagnesemia. Always discuss new supplements with your healthcare provider, especially if you take prescription medications.
Written by Greg Howlett
Frequently asked questions
What forms of Magnesium are in this Magnesium Complex?
This formula contains two organic forms: Magnesium citrate and Magnesium malate. Both are highly soluble. Research shows Magnesium citrate has 55% solubility in water and is substantially more soluble than inorganic forms like Magnesium oxide. Organic Magnesium forms are generally better absorbed by the body.
How much Magnesium does each serving provide?
Two capsules (one serving) provide 184 mg of Magnesium. The suggested use is two servings per day (2 capsules twice daily with a meal), for a total of 368 mg of supplemental Magnesium daily. The RDA for Magnesium is 400–420 mg/day for adult men and 310–320 mg/day for adult women, and this amount includes Magnesium from all sources including food.
Does this product contain vitamin D3 or zinc?
This Nature's Sunshine Magnesium Complex focuses specifically on Magnesium in citrate and malate forms. The ingredient label lists Magnesium citrate and Magnesium malate. If you are looking for a formula that also includes vitamin D3 or zinc, our naturopath can help you find a complementary product during a free consultation.
Can Magnesium supplements interact with medications?
Yes. Magnesium can decrease the absorption of bisphosphonates, tetracycline antibiotics, and quinolone antibiotics — these medications should be separated from Magnesium by at least 2 hours (4–6 hours for tetracyclines and quinolones). Loop and thiazide diuretics can deplete Magnesium, while long-term use of proton pump inhibitors may cause low Magnesium levels. Magnesium may also reduce the absorption of gabapentin by about 20%. Always consult your healthcare provider before combining supplements with prescription medications.
Who is most at risk for Magnesium deficiency?
It is estimated that 56–68% of Americans don't meet the RDA for Magnesium. Those at highest risk include older adults (due to decreased absorption and increased medication use), individuals with type 2 diabetes, people with gastrointestinal disorders, those with alcohol dependence, men over 70, and teenage girls. Early symptoms of deficiency include fatigue, weakness, loss of appetite, and muscle cramps.
Does research support Magnesium for heart health and muscle cramps?
Research suggests that higher Magnesium levels are inversely associated with risks of coronary heart disease, stroke, and total cardiovascular disease across multiple large meta-analyses. For muscle cramps, Magnesium is the most studied mineral supplement; deficiency impairs muscle relaxation, as muscles contract normally but struggle to fully release when levels are low. While the evidence is strongest for people who are Magnesium-deficient, maintaining adequate Magnesium intake supports both cardiovascular and musculoskeletal function.
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